Some negative side effects of a long-term ketogenic diet have been suggested, including increased risk of kidney stones and osteoporosis, and increased blood levels of uric acid (a risk factor for gout). Possible nutrient deficiencies may arise if a variety of recommended foods on the ketogenic diet are not included. It is important to not solely focus on eating high-fat foods, but to include a daily variety of the allowed meats, fish, vegetables, fruits, nuts, and seeds to ensure adequate intakes of fiber, B vitamins, and minerals (iron, magnesium, zinc)—nutrients typically found in foods like whole grains that are restricted from the diet. Because whole food groups are excluded, assistance from a registered dietitian may be beneficial in creating a ketogenic diet that minimizes nutrient deficiencies.
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Although in most clinical settings, BMI and waist circumference are used because they are inexpensive and convenient, it is evident that they are not able to precisely determine excess fat mass and its loss during treatment (44). More precise techniques to assess body composition are needed in specialized clinical settings and for research purposes. Therefore, another target of this work was to compare the accuracy of the information provided by the more expensive and less convenient DXA, currently considered the gold standard, with the less expensive and more convenient MF-BIA, as well as with ADP, which is only used in highly specialized centers because of its high cost (45). The results obtained showed that MF-BIA correlates very well with DXA, although with a tendency to slightly underestimate the FM%. These results are consistent with previous work that found that MF-BIA may overestimate the FFM, and thus produce an underestimation of the FM and FM% (45). MF-BIA provided highly relevant information about the water component during dieting. On the other hand, the ADP instrument showed a lower correlation with DXA and a greater variability in estimating the FM%. Compared with DXA, ADP underestimates the FM% in thinner patients, and overestimates the FM% in those patients with a higher body fat. The 3 techniques correlated remarkably well, although the less expensive MF-BIA performed with high precision.
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“The argument is that after decades of abusing your body with carbohydrates and thus creating insulin resistance, your body is not going to magically heal itself from a measly 30 days on a low-carb eating plan,” she explains. “If you need things to celebrate while you wait for the scale to start ticking down, look toward your other accomplishments—body composition, pictures, and measurements after three months.”
There are plant based healthy oils that have been in the food chain for thousands of years, including high-fat foods such as all nuts and seeds, avocados, extra virgin olive oil, sesame seed oil, black cumin seed oil (popular in the Middle East), palm oil sourced from sustainable producers, and the healthiest plant based fat of them all, coconut oil.
Klein S, Sheard NF, Pi-Sunyer S, Daly A, Wylie-Rosett J, Kulkarni K, Clark NG. Weight management through lifestyle modification for the prevention and management of type 2 diabetes: rationale and strategies. A statement of the American Diabetes Association, the North American Association for the Study of Obesity, and the American Society for Clinical Nutrition. Am J Clin Nutr. 2004;80:257–263. [PubMed] [Google Scholar]
The last technique used to determine body composition in the current study was ADP (BodPod; Life Measurements Instruments, Concord, Canada), which is accepted as a convenient alternative to the water immersion method for assessing body composition. The standard BodPod protocol was followed (24), and weekly quality control tests were performed during the study period; a second calibration was conducted immediately prior to the measurement of each participant. ADP determines body volume using Boyle’s law of the pressure/volume relationship. Therefore, body volume is equivalent to the decrease of volume in the chamber with the entrance of the patient under isothermal conditions. The participants were instructed to wear a swimming suit tight to the body and a swim cap during the test to diminish accumulated air and avoid volume discrepancies. Thoracic gas volume was measured by connecting the subject to a breathing circuit. The process was repeated until a consistent measurement was obtained. Body density was calculated as mass divided by volume and corrected for lung volume. The Siri formula was used to calculate FM, FM%, and FFM (24, 25).
Your glycogen stores can still be refilled while on a ketogenic diet. A keto diet is an excellent way to build muscle, but protein intake is crucial here. It’s suggested that if you are looking to gain mass, you should be taking in about 1.0 – 1.2g protein per lean pound of body mass. Putting muscle on may be slower on a ketogenic diet, but that’s because your total body fat is not increasing as much.5Note that in the beginning of a ketogenic diet, both endurance athletes and obese individuals see a physical performance for the first week of transition.
There is also a common worry the ketogenic diet may cause ketoacidosis, which occurs when the acidity in the blood increases. Diabetic ketoacidosis is a life-threatening condition caused by very high blood sugars and a deficiency of insulin in insulin-dependent diabetics, a very different state from ketones produced by a fat-burning metabolism on a low-carb, high-fat diet.
Eating too much for your genes/environment. I was guilty of this when I first tried keto in 2015. I made coffee with pastured butter and coconut oil every morning, ate bacon and other fatty meats, and promptly gained weight. Without getting too much in the weeds, you want to aim for a less-caloric ketogenic food plan, not a hypercaloric one like I did. Calories aren’t everything—hormones matter more—but you need to be paying attention and not overeat, which, obviously, can cause you to gain weight.
“I encourage my patients to do fasting coupled with a very-low-carbohydrate, whole-foods diet because of the astounding biochemical and clinical improvements these interventions provide, in terms of managing chronic metabolic illnesses like diabetes, hypertension, and obesity. I invite my patients to go to Diet Doctor because it is a very reliable source of information for people following a low-carbohydrate diet.”
The keto diet is a high-fat and low-carb (HFLC) diet. I would actually describe it as extremely low-carb—you're allowed to eat just 20 grams in a day. Some people on keto follow a net-carb plan (you can subtract the grams of fiber from a food's total carbs) and you're allowed to eat more carbs in a day. For my 30-day diet and for the sake of simplicity, I stuck with total carbs.
Although many hypotheses have been put forward to explain how the ketogenic diet works, it remains a mystery. Disproven hypotheses include systemic acidosis (high levels of acid in the blood), electrolyte changes and hypoglycaemia (low blood glucose).[19] Although many biochemical changes are known to occur in the brain of a patient on the ketogenic diet, it is not known which of these has an anticonvulsant effect. The lack of understanding in this area is similar to the situation with many anticonvulsant drugs.[56]
Regarding VLCK diets, there is still some distrust in their usage, despite the solid scientific evidence that supports the use of this kind of diet as a useful weight-loss therapy [13,14]. This type of diet is characterized by the restriction of carbohydrates and/or caloric intake to the point of inducing a shift in metabolism and the production of plasma ketone bodies [15,16,17]. However, it was evidenced that a VLCK diet is safe because it does not modify the acid-base equilibrium [18]. In fact, it has been proposed that the ketone body, β-hydroxy-butyrate (β-OHB) has several beneficial effects on metabolism [19] and psychological functions [20,21]. Nevertheless, a scarcity of studies has evaluated the effect of a VLCK diet combined with physical activity, on potential improvement in the psychological conditions and well-being of treated overweight/obese patients.
Every day, you will notice how simple my methods are and how the secret fat burning meal plans will speed up the fat burning process even while you rest at night. Not everyone is the same, but after the first week with the 3-Week Ketogenic Diet, most people experience one or more of the following… more energy, 5lbs lighter, joint relief, self-motivation, happiness, and a positive change in their physiological states. After 3-weeks many people have anywhere from 3-9 pounds weight loss and 7-17 inches off their waist, hips, chest, and triceps.
The ketogenic diet has been studied in at least 14 rodent animal models of seizures. It is protective in many of these models and has a different protection profile than any known anticonvulsant. Conversely, fenofibrate, not used clinically as an antiepileptic, exhibits experimental anticonvulsant properties in adult rats comparable to the ketogenic diet.[58] This, together with studies showing its efficacy in patients who have failed to achieve seizure control on half a dozen drugs, suggests a unique mechanism of action.[56]
^ Another publication of similar regimen was Hill LW, Eckman RS (1915). The Starvation Treatment of Diabetes with a series of graduated diets as used at the Massachusetts General Hospital. Boston: W.M. Leonard. This was so well received that it went into revised editions, eventually becomingThe Allen (Starvation) Treatment of Diabetes with a series of graduated diets (4th ed.). Boston. 1921. p. 140.
The ketogenic diet is used to treat drug-resistant childhood epilepsy. It has become a fad diet for people attempting to lose weight.[39] Dieters trying this often do not achieve true ketosis as this requires extreme carbohydrate restriction, and maintaining a ketogenic diet is difficult.[39][11] Some diet advocates make misleading claims that the ketogenic diet can treat or prevent cancer.[14]
The ketogenic diet first gained fame through its effectiveness for weight loss. The high-fat, low-carb diet promotes nutritional ketosis–a normal metabolic state marked by moderate levels of ketones in the blood. The idea with carb restriction in terms of weight loss is that it prompts the release of body fat to be burned or converted to ketones for energy (extra dietary fat also contributes to ketone production).
A ketogenic diet (also known as “nutritional ketosis”) is a high-fat, adequate-protein, low-carbohydrate diet. On a ketogenic diet, your brain uses ketones (a byproduct of your fat-burning metabolism) for fuel, instead of glucose.[1] Since humans can burn either glucose or ketones for energy, this change is possible to make, although there is some controversy surrounding ketogenic diets regarding both their efficacy and health benefit.[2] Ketosis keeps your body in a “fasting” or starvation metabolism, and consequently encourages weight loss by burning off fat reserves. While the shift to a ketogenic diet can be difficult initially, you should begin to see results after a few weeks.
The classic ketogenic diet is not a balanced diet and only contains tiny portions of fresh fruit and vegetables, fortified cereals, and calcium-rich foods. In particular, the B vitamins, calcium, and vitamin D must be artificially supplemented. This is achieved by taking two sugar-free supplements designed for the patient's age: a multivitamin with minerals and calcium with vitamin D.[18] A typical day of food for a child on a 4:1 ratio, 1,500 kcal (6,300 kJ) ketogenic diet comprises three small meals and three small snacks:[28]

The IWQOL-Lite, a shorter form of the original questionnaire, assesses the impact of weight on quality of life in individuals exploring treatments for weight loss. The IWQOL-Lite includes 31 statements that start with “Because of my weight…” with response options to each statement ranging from (1) “Never true” to (5) “Always true” that measure the impact of weight on 5 domains (i.e., physical function, self-esteem, sexual life, public distress, and work life). A score is calculated for each domain for each patient who answers at least 50% of the questions in any given domain. A total score is calculated if patients have responded to at least 26 out of the 31 questions. The total score is the sum of the raw scores of the 5 subscales. Raw scores (higher scores indicate poorer quality of life on the IWQOL-Lite) are converted into a T-score (0–100), with 100 representing the best possible health. Mean and standard deviations are reported for each domain [32].
Collagen is a type of protein that has been shown to suppress appetite[*], provide fullness compared to other proteins like whey, casein, or soy[*], help retain muscle mass[*] and even help to reduce the appearance of cellulite due to it’s ability to improve skin elasticity and thickness[*]. Refer to this article for more information on the benefits of collagen and the best way to supplement it in your diet.

I’ve been trying this keto diet that my dr.and daughter recommended, it’s been close to a week. I’ve changed my food intake, no bad carbs that I know of, was a huge chip addict stopped all that with no cravings. I’m not seeing any results I’m getting discouraged and everything sounds so complicated watching this, measuring that, I don’t have a clue what I’m doing. just that I stopped bread,pasta,poratoes,rice all those kind of carbs.I’m drinking more water eating green vegetables and trying to increase my fat intake. I don’t feel motivated to exercise which probably doesn’t help and have 100-130 to lose. I need help I don’t understand or have the time create a lot of meals and measure my fat,protein and carb intake.
In the absence of CHO, however, the body must shift to fat as the primary energy source. In this case, the body catabolizes stored triglycerides, which exist in abundance in even the leanest individual. In effect, the KD provokes a physiological stimulus, i.e., CHO restriction, that mimics starvation. Due to the limited ability to store or produce CHO during periods of starvation, the body thus switches to ketogenesis, the production of ketone bodies as a primary fuel source (3).
The ketosis produced by fasting or limiting carbohydrate intake does not have negative effects for most people once the body has adapted to that state. The ketosis caused by diet has been referred to as dietary ketosis, physiological ketosis, benign dietary ketosis (Atkins), and, most recently, nutritional ketosis (Phinney and Volek), in an attempt to clear up possible confusion with diabetic ketoacidosis.
Keto runs counter to many of the low-fat diet fads of the 1980s and 1990s: It actually emphasizes fat. “That is hard to comprehend because we don’t eat anything that’s pure fat, says Kristen Mancinelli, RD, author of The Ketogenic Diet. “We don’t eat a stick of butter or a spoonful of olive oil or even a nice cup of lard. That would be unpleasant, so we really have a hard time wrapping our heads around this concept of the ketogenic diet.”

Dr. Campos, it is unfortunate that you retain the medical community’s negative stance on the ketogenic diet, probably picked up in medical school when you studied ketoacidosis, in the midst of an obesity and type II diabetes epidemic that is growing every year, especially among populations who will never see the Harvard Health Letter. The medical community has failed in reversing this trend, especially among children, and the public is picking up the tab, in the form of higher health insurance premiums to treat chronic metabolic diseases which doctors cannot cure. The ketogenic diet does not bid its adherents to eat unhealthy processed meats, and the green leafy vegetables that it emphasizes are important in a number of nutritional deficiencies. People lose weight on the ketogenic diet, they lose their craving for sugar, they feel more satiety, they may become less depressed, their insulin receptors sensitivity is improved, and these are all the good outcomes you fail to mention. There is a growing body of research which demonstrates the neuroprotective effects of the ketogenic diet to slow cancer progression, as well as diseases like Parkinson’s and Alzheimer’s, for which there are no effective medical treatments. Please respect your patients by providing them with evidence-based medical outcomes, not opinions.
During this study, the patients followed the different steps of the method until they reached the target weight or up to a maximum of 4 months of follow-up, although patients remained under medical supervision for the following months. Patients visited the research team every 15 ± 2 days to control adherence and evaluate potential side effects. Complete anthropometric, body composition, biochemical and phycological assessments were performed at four of the visits which were made according to the evolution of each patient through the steps of ketosis and weight loss: Visit 1 (baseline), visit 2 (maximum ketosis), visit 3 (reduced ketosis) and visit 4 (Endpoint).
Hey Patricia, you definitely want to fill up on fat and make that the majority of your calories. Fat is very satiating so you will probably get fuller, faster compared to when you would eat carbs. However, if you are eating an excessive amount of fat (past your satiety level) than it has to go somewhere and anything in extreme excess will be most likely be stored in your body as body fat. I recommend eating to satiety and if you are not seeing results, you may have to track your consumption for a few weeks so you have a better idea of how much you’re consuming and what works best for your goals. Our macro calculator can help get you started with that if you’d like: https://perfectketo.com/keto-macro-calculator/
Some people on a keto or low carb diet choose to count total carbs instead of net carbs. This makes it more difficult to fit in more leafy greens and low carb vegetables (which are filled with fiber), so you should only try that if you don’t get results with a net carb method. And, start with reducing sugar alcohols and low carb treats before deciding to do a “total carbs” method.
In the 1990s, Atkins published an update from his 1972 book, Dr. Atkins New Diet Revolution, and other doctors began to publish books based on the same principles. This has been said to be the beginning of what the mass media call the "low carb craze" in the United States.[59] During the late 1990s and early 2000s, low-carbohydrate diets became some of the most popular diets in the US. By some accounts, up to 18% of the population was using one type of low-carbohydrate diet or another at the peak of their popularity.[60] Food manufacturers and restaurant chains like Krispy Kreme noted the trend, as it affected their businesses.[61] Parts of the mainstream medical community have denounced low-carbohydrate diets as being dangerous to health, such as the AHA in 2001[62] and the American Kidney Fund in 2002[63] Low-carbohydrate advocates did some adjustments of their own, increasingly advocating controlling fat and eliminating trans fat.[64]
Combine that with the fact that your body is excreting more water, and you have a potential recipe for clogged pipes. You can keep things moving by getting some fiber from keto-friendly foods like avocado, nuts, and limited portions of non-starchy vegetables and berries, says David Nico, PhD, author of Diet Diagnosis. Upping your water intake helps, too.
Long-term compliance is low and can be a big issue with a ketogenic diet, but this is the case with any lifestyle change.  Even though the ketogenic diet is significantly superior in the induction of weight loss in otherwise healthy patients with obesity and the induced weight loss is rapid, intense, and sustained until at least 2 year, the understanding of the clinical impacts, safety, tolerability, efficacy, duration of treatment, and prognosis after discontinuation of the diet is challenging and requires further studies to understand the disease-specific mechanisms.
“I discovered the low-carb, ketogenic diet some four years ago and saw huge improvements in my own health. After establishing that it is based on sound scientific principles I felt compelled to offer it to my patients. We recommend the Diet Doctor website as it offers an unbiased, contemporary source of reliable low-carb ketogenic advice. It is easy to use and you can rely on its integrity.”
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