Despite the efforts to decrease weight loss, obesity prevalence is increasing worldwide [36]. The obesogenic environment and the unsuccessful effect of current treatments are consistently contributing to an increase in obesity prevalence. Obesity is promoted by several factors, including genetic, environmental, metabolic, and behavioral factors [8,11,37]. These same factors are involved in the unsuccessful effect of many weight-loss therapies [38]. Apart from the biochemical and genetic factors, in the literature, obesity has consistently been related with a poorer quality of life [39] and lower self-esteem and lower life satisfaction [40]. Additionally, food addiction was proposed as a plausible causal factor contributing to obesity and weight regain after a weight-loss therapy, at least in the same individuals [41]. Therefore, it is important to control these factors to attain success in weight-loss therapy. In this context, a VLCK diet has previously been shown to induce severe body-weight loss that has been maintained for at least 2 years after dieting [6]. This nutritional weight-loss method resulted in the beneficial effects of decreasing body fat mass by preserving body muscle mass and strength [4] and maintaining the resting metabolic rate [7]. Thus, the new open question was whether the beneficial effects of this nutritional method on body composition and energy metabolism are associated with a modulation in the psychobiological phenomena of obese patients.

In general, you want to eat the minimum amount of protein to preserve lean body mass and not overtax your kidneys. If you eat too much protein, the excess converts to glucose through a process called gluconeogenesis. You don’t want that to occur in ketosis. Instead, eat anti-inflammatory protein—at the minimum amount to preserve or build lean body mass. My favorite sources are wild-caught fish, grass-fed and -finished beef and wild meats (elk, bison, etc.), pasture-raised poultry, nuts, and seeds. Make sure fish has more selenium (which helps protect the brain) than mercury, to mitigate heavy metal toxicity. Good sources that have a safe selenium/mercury ratio include: tuna, opah, wahoo, spearfish, swordfish.
While you’re focusing on fat, protein, and carbs, you should also make sure you’re getting adequate fiber. “People often assume that they should only eat things like meat and butter on the ketogenic diet,” says Farshad Fani Marvasti, MD, an associate professor and director of Public Health, Prevention, and Health Promotion at the University of Arizona College of Medicine in Phoenix. “You should make sure you are eating enough vegetables because you need the fiber.”
“I am a physician with type 1 diabetes. I have been using a low-carb, ketogenic diet to treat my own diabetes for the past 16 years. Evidence shows that low-carb diets are safe and effective. With the potential to reverse type 2 diabetes, control type 1 diabetes and even stop, slow down, or reverse complications, a low-carb diet can be life changing. Diet Doctor provides the most accurate and relevant materials for a healthy, easy and fun low-carb experience.”
Weight loss is the primary reason my patients use the ketogenic diet. Previous research shows good evidence of a faster weight loss when patients go on a ketogenic or very low carbohydrate diet compared to participants on a more traditional low-fat diet, or even a Mediterranean diet. However, that difference in weight loss seems to disappear over time.
“I recommend the low-carb diet and other lifestyle changes to reverse obesity, diabetes, hypertension and PCOS at our health wellness centre. The prevalence of food and lifestyle-related diseases in a developing country like Tanzania is increasing at an alarming rate. Evidence-based scientific approaches combined with low carb have been my basic tools to reverse diabetes, hypertension, obesity and many other metabolic diseases.”

Women were also invited to complete a questionnaire on sexual function (the Female Sexual Function Index—FSFI). The FSFI consists of 19 questions, divided into 6 domains: desire, arousal, lubrication, orgasm, satisfaction, and pain. Each answer is rated on a scale ranging from 0 to 5 or 1 to 5 (0 means no sexual activity in the four preceding weeks) [28]. The total FSFI score, obtained from the sum of the items in each domain multiplied by the domain factor (0.6 for desire, 0.3 for arousal and lubrication, and 0.4 for orgasm, satisfaction, and pain), may range from 2.0 to 36.0. Lower scores indicate poorer sexual function. A total FSFI score less than 26.55 is indicative of sexual dysfunction [28].

Wondering what fits into a keto diet — and what doesn’t? “It’s so important to know what foods you’ll be eating before you start, and how to incorporate more fats into your diet,” says Kristen Mancinelli, RD, author of The Ketogenic Diet: A Scientifically Proven Approach to Fast, Healthy Weight Loss, who is based in New York City. We asked her for some guidelines.
Blanket statement: It’s always best to check with your doctor before starting on this regimen. With that said, “the keto diet isn’t recommended for those with liver or kidney disease, or someone with a medical condition, such as a gastrointestinal issue, who can’t metabolize high amounts of dietary fat,” says Sarah Jadin, a Los-Angeles based registered dietitian and founder of Keto Consulting, LLC. If you’ve had your gallbladder removed, the keto diet may be a no-go. Women who are pregnant or breastfeeding and people with certain rare genetic disorders shouldn’t try this diet.
Adding heavy cream or half-and-half to your coffee is one way to get an additional source of fat into your day, says Keatley. Just realize that it is a source of saturated fat — and, given the small serving size, it’s easy to go overboard. According to the USDA, 1 tbsp has 51 calories, 5 g of fat (3.5 g saturated fat), and is just shy of ½ g of carbohydrate.
Your dietary needs change dramatically with keto. Sodium becomes a critical nutrient, as do magnesium and potassium. “At least in the initial stages of being on the keto diet, you will urinate more. One of the key electrolytes lost through urination is magnesium,” says Carolyn Dean, MD, ND, a health and nutrition expert and author of The Magnesium Miracle. “Magnesium is an energy mineral, which will help you burn fat and lose weight.”

“I am determined to shatter the chiding “eat less, exercise more” obesity medicine paradigm. Obesity is not a personal failure, but a chronic health condition unfolding in our country and around the world. It is a result of the “carboholic” society we live in. Through a holistic approach, I arm patients with knowledge, tools, and skills to manage their weight as well as their overall health.”
1. Reduce carbs. How much? The short answer is to eat 20 to 25 grams each day for weight loss, and 25 to 30 for weight maintenance. (You must use a nutrition calculator for macronutrients to get it right because thinking in terms of grams is not intuitive, and nutritional ketosis is less likely to be successful if you try to “eyeball” the amounts.) The long answer is: it depends. I encourage people to limit carbs until they are in ketosis, as confirmed with a blood ketone meter (see below), and then try increasing the amount of carbs by 5 grams to see if they stay in ketosis.
Instead of getting that store-bought can of frosting that’s filled with sugar, food coloring, and trans fats, make your own! Cream cheese and butter come together perfectly to create a rich and creamy frosting that makes all of your cakes taste better. If you want an example of a great cream cheese frosting (with added fruit compote), check out our Low Carb Spice Cakes with Cream Cheese Frosting.

Hey Michael, I would avoid it when just starting off because the carbs can add up fast and mostly of the canned whipped creams are full of additives. Once you’re adapted, I’d recommend making whipped cream from scratch and adding a dash of stevia or other keto-friendly sweetener. It’s super easy and much healthier than the canned versions (also tastes 1000x better!)


Although these are just some studies on the low carb high fat and ketogenic diets, it is also important to mention there are thousands of published studies on this topic and many, many more are still in progress and unpublished. With time and as technology advances, we can find more proofs that the Ketogenic Diet’s benefits will be further cemented.
Typically you want to stay away from any brands that use filler ingredients like maltodextrin and dextrose, or high glycemic sweeteners like maltitol. Many low-carb products that claim low net carbs usually use these sugar alcohols. Many candies that are “sugar-free” also use these sweeteners. Avoid them where possible. These specific sweeteners respond in our body in a similar way sugar does.
Requires an adaptation process. Getting keto adapted can take one to two weeks and the transition can be uncomfortable for some people. The “Keto Flu” is commonly used to describe flu-like symptoms associated with the transition process: headaches, fatigue, nausea, etc. Due to restricted carb intake, your body is not retaining as much water so loss of electrolytes is common. This can easily be rectified with taking mineral supplements or exogenous ketones, such as the beta hydroxybutyrate mineral salts in KetoLogic® BHB [16].

You can approach keto in a number of different ways. On some keto diets, like dirty keto, it doesn’t matter where your fats, protein, and carbs come from. So dinner could be a bunless cheeseburger with extra bacon. Eating bad fats like low-quality vegetable oils, packaged low-carb snacks, and processed cheese dials up inflammation, making weight loss more challenging.[8]


Regarding VLCK diets, there is still some distrust in their usage, despite the solid scientific evidence that supports the use of this kind of diet as a useful weight-loss therapy [13,14]. This type of diet is characterized by the restriction of carbohydrates and/or caloric intake to the point of inducing a shift in metabolism and the production of plasma ketone bodies [15,16,17]. However, it was evidenced that a VLCK diet is safe because it does not modify the acid-base equilibrium [18]. In fact, it has been proposed that the ketone body, β-hydroxy-butyrate (β-OHB) has several beneficial effects on metabolism [19] and psychological functions [20,21]. Nevertheless, a scarcity of studies has evaluated the effect of a VLCK diet combined with physical activity, on potential improvement in the psychological conditions and well-being of treated overweight/obese patients.
“I encounter many patients who are interested in LCHF and are finding benefit in weight reduction, better diabetes control, improved endurance and energy levels, and improved lipid profiles. There is a great deal of confusion out there about the diet, much of it based on outdated science or an incomplete understanding of the topic. I feel that I owe it to patients to be informed about LCHF so that I can advise them on the risks and benefits it could have for them.”
Very low calorie diets, or VLCDs, are supervised medical programs designed to bring about rapid weight loss in people who are dangerously overweight or morbidly obese. They typically involve you taking specially prepared formulas, usually liquid shakes, to replace all your meals for several weeks to a few months. Because they are meal replacements, they also contain a balance of nutrients to provide you with all the vitamins and minerals you need, but also just enough calories to prevent your body to clinging to fat because it thinks you are starving. By definition, a VLCD involves consuming about 800 calories per day.
Carbohydrates have been linked to this skin condition, so cutting down on them may help. And the drop in insulin that a ketogenic diet can trigger may also help stop acne breakouts. (Insulin can cause your body to make other hormones that bring on outbreaks.) Still, more research is needed to determine exactly how much effect, if any, the diet actually has on acne. 
A popular keto supplement are exogenous ketones (popularly called “keto diet pills”) that may help you achieve results earlier as well as remain in that state. (Don’t confuse exogenous ketones with raspberry ketones, as the latter don’t raise ketone levels in the body or mimic endogenous ketones, so you wouldn’t use raspberry ketones in your regimen.)
“After years of practicing Family & Sports Medicine, I’ve recognized that preventing and addressing my patients’ dietary metabolic issues are the foundation upon which quality medical and musculoskeletal care are built. LCHF principles produced such remarkable results in my patients that I completely redefined my scope of practice and developed a unique Lifestyle Medicine Program that synergistically complements my Sports Medicine & Non-Surgical Orthopedics specialty practice. I truly care for the whole person. Diet Doctor is an exceptional, comprehensive resource for lay persons and clinicians; I recommend it to all my patients and colleagues.”
Fanatic? Someone with T2D, a disease usually claimed to be progressive and a never ending stream of problems and medications, was REVERSED. That’s something to shout from the rooftops. The drop in medication use alone, but the big pharma companies would prefer that people’s stories of reversing (well, putting it into remission) T2D get called fanatical instead of insightful.

ATTENTION: If you speak English, assistance services, free of charge, are available to you. Call (877) 285-6920; TTY: (877) 893-8199. For assistance in the following languages: العربية | | 中文 | Nederlands | Français | Deutsche | ελληνικά | ગુજરાતી | हिंदी | Italiano | 日本語 | 한국어 | ਪੰਜਾਬੀ | Pennsylvania Nederlands | Polskie | русский | Español | Pilipino | اردو | Tiếng Việt
Though technically a fruit, avocados offer a rich source of heart-healthy monounsaturated fatty acids (MUFAs). They're also packed with fiber to bolster digestive health. One-half of an avocado contains 161 calories, 2 grams (g) of protein, 15 g of fat, 9 g of total carbs, and 7 g of fiber (bringing it to 2 g of net carbs), notes the U.S. Department of Agriculture (USDA).

Requires an adaptation process. Getting keto adapted can take one to two weeks and the transition can be uncomfortable for some people. The “Keto Flu” is commonly used to describe flu-like symptoms associated with the transition process: headaches, fatigue, nausea, etc. Due to restricted carb intake, your body is not retaining as much water so loss of electrolytes is common. This can easily be rectified with taking mineral supplements or exogenous ketones, such as the beta hydroxybutyrate mineral salts in KetoLogic® BHB [16].


On a “strict” (standard) keto diet, fats typically provides about 70 percent to 80 percent of total daily calories, protein about 15 percent to 20 percent, and carbohydrates just around 5 percent. However, a more “moderate” approach to the keto diet is also a good option for many people that can allow for an easier transition into very low-carb eating and more flexibility (more on these types of plans below).
“I discovered the low-carb, ketogenic diet some four years ago and saw huge improvements in my own health. After establishing that it is based on sound scientific principles I felt compelled to offer it to my patients. We recommend the Diet Doctor website as it offers an unbiased, contemporary source of reliable low-carb ketogenic advice. It is easy to use and you can rely on its integrity.”

In general, you want to eat the minimum amount of protein to preserve lean body mass and not overtax your kidneys. If you eat too much protein, the excess converts to glucose through a process called gluconeogenesis. You don’t want that to occur in ketosis. Instead, eat anti-inflammatory protein—at the minimum amount to preserve or build lean body mass. My favorite sources are wild-caught fish, grass-fed and -finished beef and wild meats (elk, bison, etc.), pasture-raised poultry, nuts, and seeds. Make sure fish has more selenium (which helps protect the brain) than mercury, to mitigate heavy metal toxicity. Good sources that have a safe selenium/mercury ratio include: tuna, opah, wahoo, spearfish, swordfish.
Introducing @lowcarbjourney_jf: Hi there, my name is Jordynn, I have lost just over 60lbs using keto diet, started in early November 😊 getting married in 2019, and looking to be my best self! My goal is to lose 100-110lbs total. . . . #myketotransformation #fitspiration #weightloss #weightlossjourney #ketofam #weightlossmotivation #transformation #fitfam #weightlosstransformation #extremeweightloss #fitness #instafit #inspiration #motivation #fitnessmotivation #beforeandafter #diet #exercise #trainandtransform #beforeandafterweightloss #biggestloser #keto #lowcarb #lchf #ketotransformations
“As a family physician, I have been recommending a low carbohydrate diet to all my patients. Truthfully, I cannot recommend any other diet with a clear conscience. I discovered the scientific benefits of a low-carb diet from Diet Doctor in 2011 when I was looking for new and better ways to manage my patients with diabetes, and I have never looked back since. My patients have benefited immensely from this diet, and it’s the best way to manage obesity, PCOS, metabolic syndrome, insulin resistance and diabetes. To me, Diet Doctor is the one-stop website for everything low-carb.”
Dr. Jockers, thank you so much for this clear and detailed article! I began a keto-style diet around August 2019. By late November, I had fallen from 197 lbs. to under 175 lbs., dropped from 28% to 18% body fat, and anecdotally felt much better in all aspects of my health. All of this occurred exclusively due to diet, I believe– I had almost no exercise routine to speak of, and my desk-based job is pretty sedentary. My family practice doc was surprised and happy with the results as well when I met with him in January… until my blood work came back showing total cholesterol at 257, triglycerides at 236, LDL-C at 162, and HDL at 50.

Those who’ve had their gallbladder removed may need ox bile supplementation to support their body in breaking down fats[*] and aid in overall digestion. When taken with a meal, ox bile provides a concentrated source of bile which takes the place of the bile that would have been secreted by your gallbladder. As mentioned before, proper digestion is key to helping aid in weight loss and optimizing overall health and wellness.
I get many questions about intermittent fasting, the health benefits, the weight loss benefits, and the like. People normally use intermittent fasting for both the energy and mental clarity it can offer. But it’s not just good for that. It can offer breakthroughs of plateaus and even benefits in nutrient uptake in exercise. We go more in depth to intermittent fasting in Week 3 and 4, so keep your eyes peeled!
×